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AbbVie's Rinvoq (upadacitinib) Receives ANVISA's Approval for Rheumatoid Arthritis

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AbbVie's Rinvoq (upadacitinib) Receives ANVISA's Approval for Rheumatoid Arthritis

Shots:

  • The approval is based on five P-III studies of SELECT program- assessing Rinvoq in ~4-400 patients- including in Brazil
  • The studies resulted in meeting its 1EPs & 2EPs. In SELECT COMPARE study- @12wks- 29% of patients receiving Rinvoq + MTX (methotrexate) achieved remission assessed by the DAS28 - PCR index
  • Rinvoq (PO- qd) is JAK inhibitor- indicated to treat active- moderate to severe RA- who did not respond adequately or who were intolerant to one or more DMARD

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Ref: PRNewswire | Image:abbvie


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